What is the quickest way to get to Virginia from Durham?
ANSWER PERSON RESPONDS: Are you looking for the quickest way to purchase a lottery ticket? Go straight up US 501 (Duke Street or Roxboro Rd.) due north through Roxboro. You hit the border just south of South Boston, VA. The border is about 40-45 miles, but you do have some stop lights on the way. If there are no convenience stores at the state line on US 501, then at Roxboro you need to veer slightly to the NE onto NC 49 to head to the town of Virgilina, which straddles the border.